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1

Genetic Analysis of the Multidrug Transporter

Gottesman, M. M., Hrycyna, C. A., Schoenlein, P. V., Germann, U. A., Pastan, I.

Journal:

Annual Review of Genetics

Year:

1995

Language:

english

File:

PDF, 2.24 MB

english, 1995

2

Design and Evaluation of a One-Semester General Chemistry Course for Undergraduate Life Science Majors

Schnoebelen, Carly, Towns, Marcy H., Chmielewski, Jean, Hrycyna, Christine A.

Journal:

Journal of Chemical Education

Year:

2018

Language:

english

File:

PDF, 564 KB

english, 2018

3

Non-substrate based, small molecule inhibitors of the human isoprenylcysteine carboxyl methyltransferase

Butler, Kyle V., Bohn, Kelsey, Hrycyna, Christine A., Jin, Jian

Journal:

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

4

BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER1

Ambudkar, Suresh V., Dey, Saibal, Hrycyna, Christine A., Ramachandra, Muralidhara, Pastan, Ira, Gottesman, Michael M.

Journal:

Annual Review of Pharmacology

Year:

1999

Language:

english

File:

PDF, 467 KB

english, 1999

5

Competency-Based Reforms of the Undergraduate Biology Curriculum: Integrating the Physical and Biological Sciences

Thompson, K. V., Chmielewski, J., Gaines, M. S., Hrycyna, C. A., LaCourse, W. R.

Journal:

Cell Biology Education

Year:

2013

Language:

english

File:

PDF, 274 KB

english, 2013

6

A Protease for the Ages

Michaelis, S., Hrycyna, C. A.

Journal:

Year:

2013

Language:

english

File:

PDF, 331 KB

english, 2013

7

Inhibition of Membrane-Associated Methyltransferases by a Cholesterol-Based Metal Chelator

Hodges, Heather B., Zhou, Mingkang, Haldar, Saubhik, Anderson, Jessica L., Thompson, David H., Hrycyna, Christine A.

Journal:

Bioconjugate Chemistry

Year:

2005

Language:

english

File:

PDF, 86 KB

english, 2005

8

Cosmological dynamics with non-minimally coupled scalar field and a constant potential function

Hrycyna, Orest, Szydłowski, Marek

Journal:

Journal of Cosmology and Astroparticle Physics

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

9

[Methods in Enzymology] Lipid Modifications of Proteins Volume 250 || [21] Yeast STE 14 methyltransferase, expressed as TrpE-STE 14 fusion protein in Escherichia coli, for in Vitro Carboxylmethylation of prenylated polypeptides

Hrycyna, Christine A.

Year:

1995

Language:

english

File:

PDF, 801 KB

english, 1995

10

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Wang, Chao, Zhang, Bin, Ratliff, Anna C., Arrington, Justine, Chen, Jingjuan, Xiong, Yan, Yue, Feng, Nie, Yaohui, Hu, Keping, Jin, Wen, Tao, W. Andy, Hrycyna, Christine A., Sun, Xiaobo, Kuang, Shihuan

Journal:

The FASEB Journal

Year:

2019

Language:

english

File:

PDF, 2.78 MB

english, 2019

11

Effect of combination of suboptimal concentrations of P-glycoprotein blockers on the proliferation of MDR1 gene expressing cells

Myungsil Hwang, Chang-Ho Ahn, P. Scott Pine, Jun-Jie Yin, Christine A. Hrycyna, Thomas Licht, Adorjan Aszalos

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

12

Toward Eradicating HIV Reservoirs in the Brain: Inhibiting P-Glycoprotein at the Blood–Brain Barrier with Prodrug Abacavir Dimers

Emmert, Dana, Davis, David A., Campos, Christopher, Miller, David S., Hrycyna, Christine A., Chmielewski, Jean, Namanja, Hilda A.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 289 KB

english, 2012

13

Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum

Hrycyna, Christine A., Summers, Robert L., Lehane, Adele M., Pires, Marcos M., Namanja, Hilda, Bohn, Kelsey, Kuriakose, Jerrin, Ferdig, Michael, Henrich, Philipp P., Fidock, David A., Kirk, Kiaran, Ch

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 950 KB

english, 2014

14

Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24

CORRIGAN, Douglas P., KUSZCZAK, Danuta, RUSINOL, Antonio E., THEWKE, Douglas P., HRYCYNA, Christine A., MICHAELIS, Susan, SINENSKY, Michael S.

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 402 KB

english, 2005

15

Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes

Kalub Hahne, Jeffrey S. Vervacke, Liza Shrestha, James L. Donelson, Richard A. Gibbs, Mark D. Distefano, Christine A. Hrycyna

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 417 KB

english, 2012

16

Functional Reconstitution of the Integral Membrane Enzyme, Isoprenylcysteine Carboxyl Methyltransferase, in Synthetic Bolalipid Membrane Vesicles †

Febo-Ayala, Wilma, Morera-Félix, Shakira L., Hrycyna, Christine A., Thompson, David H.

Journal:

Year:

2006

Language:

english

File:

PDF, 257 KB

english, 2006

17

Implementation of diverse non-centrosymmetric layer concepts for tuning the interface activity of a magnesium alloy

Stamboroski, Stephani, Stachera, Priscilla Natalli, Ureña, Yendry Regina Corrales, Hrycyna, Gustavo Homann, Neto, Wilson Iraja Taborda Ribas, de Azambuja, Wagner Kazuki, Salz, Dirk, Ihde, Jörg, Noeske

Journal:

Applied Adhesion Science

Year:

2016

Language:

english

File:

PDF, 4.05 MB

english, 2016

18

Dissipative or conservative cosmology with dark energy?

Marek Szydłowski, Orest Hrycyna

Journal:

Annals of Physics

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

19

Oligomerization of the Human ABC Transporter ABCG2: Evaluation of the Native Protein and Chimeric Dimers †

Bhatia, Aarti, Schäfer, Hans-Jochen, Hrycyna, Christine A.

Journal:

Year:

2005

Language:

english

File:

PDF, 523 KB

english, 2005

20

[Methods in Enzymology] ABC Transporters: Biochemical, Cellular, and Molecular Aspects Volume 292 || [33] Functional expression of human P-glycoprotein from plasmids using vaccinia virus-bacteriophage T7 RNA polymerase system

Hrycyna, Christine A.

Year:

1998

Language:

english

File:

PDF, 839 KB

english, 1998

21

Contribution to Substrate Specificity and Transport of Nonconserved Residues in Transmembrane Domain 12 of Human P-Glycoprotein †

Hafkemeyer, Peter, Dey, Saibal, Ambudkar, Suresh V., Hrycyna, Christine A., Pastan, Ira, Gottesman, Michael M.

Journal:

Year:

1998

Language:

english

File:

PDF, 309 KB

english, 1998

22

Extended quintessence with nonminimally coupled phantom scalar field

Hrycyna, Orest, Szydłowski, Marek

Journal:

Physical Review D

Year:

2007

Language:

english

File:

PDF, 1.16 MB

english, 2007

23

model

Hrycyna, Orest, Szydłowski, Marek

Journal:

Physical Review D

Year:

2013

Language:

english

File:

PDF, 150 KB

english, 2013

24

Human P-Glycoprotein Exhibits Reduced Affinity for Substrates during a Catalytic Transition State †

Ramachandra, Muralidhara, Ambudkar, Suresh V., Chen, David, Hrycyna, Christine A., Dey, Saibal, Gottesman, Michael M., Pastan, Ira

Journal:

Year:

1998

Language:

english

File:

PDF, 302 KB

english, 1998

25

Purification, Functional Reconstitution, and Characterization of the Saccharomyces cerevisiae Isoprenylcysteine Carboxylmethyltransferase Ste14p

Anderson, J. L., Frase, H., Michaelis, S., Hrycyna, C. A.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 802 KB

english, 2005

26

Non-minimally coupled scalar field cosmology on the phase plane

O. Hrycyna, M. Szydłowski

Year:

2009

Language:

english

File:

PDF, 564 KB

english, 2009

27

Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine

Namanja-Magliano, Hilda A., Bohn, Kelsey, Agrawal, Neha, Willoughby, Meghan E., Hrycyna, Christine A., Chmielewski, Jean

Journal:

Bioorganic & Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 472 KB

english, 2017

28

Different faces of chaos in FRW models with scalar fields—geometrical point of view

Orest Hrycyna, Marek Szydłowski

Journal:

Chaos, Solitons & Fractals

Year:

2006

Language:

english

File:

PDF, 1.93 MB

english, 2006

29

Bivalent Probes of the Human Multidrug Transporter P-Glycoprotein

Pires, Marcos M., Hrycyna, Christine A., Chmielewski, Jean

Journal:

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

30

Solid-Phase Synthesis of Prenylcysteine Analogs

Donelson, James L., Hodges-Loaiza, Heather B., Henriksen, Brian S., Hrycyna, Christine A., Gibbs, Richard A.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 422 KB

english, 2009

31

Dual Modulation of Human P-Glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood–Brain Barrier

Bohn, Kelsey, Lange, Allison, Chmielewski, Jean, Hrycyna, Christine A.

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

32

[ 3 H]Dexamethasone Binding to Plasma Membrane-Enriched Fractions from Liver of Nonadrenalectomized Rats*

QUELLE, FREDERICK W., SMITH, RICHARD V., HRYCYNA, CHRISTINE A., KALIBAN, TIMOTHY D., CROOKS, JOAN A., O'BRIEN, JANE M.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.22 MB

english, 1988

33

Lipid and sulfur substituted prenylcysteine analogs as human Icmt inhibitors

Joel A. Bergman, Kalub Hahne, Christine A. Hrycyna, Richard A. Gibbs

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

34

Amide-modified prenylcysteine based Icmt inhibitors: Structure–activity relationships, kinetic analysis and cellular characterization

Jaimeen D. Majmudar, Heather B. Hodges-Loaiza, Kalub Hahne, James L. Donelson, Jiao Song, Liza Shrestha, Marietta L. Harrison, Christine A. Hrycyna, Richard A. Gibbs

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.81 MB

english, 2012

35

S -Farnesyl-Thiopropionic Acid Triazoles as Potent Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase

Bergman, Joel A., Hahne, Kalub, Song, Jiao, Hrycyna, Christine A., Gibbs, Richard A.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 475 KB

english, 2012

36

Dynamic Combinatorial Libraries of 2,5-Diformylfuran-Derived Macrocycles

Ziach, Krzysztof, Obrocka-Hrycyna, Aleksandra, Jurczak, Janusz

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 546 KB

english, 2014

37

Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae.

Hrycyna, C A, Clarke, S

Journal:

Molecular and Cellular Biology

Year:

1990

Language:

english

File:

PDF, 1.06 MB

english, 1990

38

Functional Oligomerization of the Saccharomyces cerevisiae Isoprenylcysteine Carboxyl Methyltransferase, Ste14p

Griggs, A. M., Hahne, K., Hrycyna, C. A.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 1.37 MB

english, 2010

39

a-Factor analogues containing alkyne- and azide functionalized isoprenoids are efficiently enzymatically processed and retain wild type bioactivity

Diaz-Rodriguez, Veronica, Hsu, Erh-Ting, Ganusova, Elena, Werst, Elena, Becker, Jeffrey Marvin, Hrycyna, Christine A., Distefano, Mark D.

Journal:

Bioconjugate Chemistry

Year:

2017

Language:

english

File:

PDF, 6.54 MB

english, 2017

40

Route to Lambda in conformally coupled phantom cosmology

Orest Hrycyna, Marek Szydłowski

Journal:

Physics Letters B

Year:

2007

Language:

english

File:

PDF, 349 KB

english, 2007

41

From model dynamics to oscillating dark energy parameterisation

Aleksandra Kurek, Orest Hrycyna, Marek Szydłowski

Journal:

Physics Letters B

Year:

2010

Language:

english

File:

PDF, 400 KB

english, 2010

42

Functional Characterization of Glycosylation-Deficient Human P-Glycoprotein Using A Vaccinia Virus Expression System

J.J. Gribar, M. Ramachandra, C.A. Hrycyna, S. Dey, S.V. Ambudkar

Journal:

Journal of Membrane Biology

Year:

2000

Language:

english

File:

PDF, 569 KB

english, 2000

43

A general fluorescence-based coupled assay for S-adenosylmethionine-dependent methyltransferases

Caihua Wang, Scott Leffler, David H. Thompson, Christine A. Hrycyna

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

44

Structural Flexibility of the Linker Region of Human P-Glycoprotein Permits ATP Hydrolysis and Drug Transport †

Hrycyna, Christine A., Airan, Lisa E., Germann, Ursula A., Ambudkar, Suresh V., Pastan, Ira, Gottesman, Michael M.

Journal:

Year:

1998

Language:

english

File:

PDF, 220 KB

english, 1998

45

Research Spotlight: Tools for eradicating HIV in the brain: prodrug dimeric inhibitors of P-gp

Chmielewski, Jean, Hrycyna, Christine

Journal:

Therapeutic Delivery

Year:

2012

Language:

english

File:

PDF, 427 KB

english, 2012

46

Infracommunities of bat flies (Diptera: Streblidae and Nycteribiidae) of bats (Mammalia: Chiroptera) in three conservation units in the State of Amapá, Brazil

Hrycyna, Gabriela, Martins, Ana Carolina Moreira, Graciolli, Gustavo

Journal:

Biota Neotropica

Year:

2019

File:

PDF, 455 KB

2019

47

Potential tools for eradicating HIV reservoirs in the brain: the development of Trojan horse prodrugs for the inhibition of P-glycoprotein with anti-HIV-1 activity

Agrawal, Neha, Rowe, Jennifer, Lan, Jie, Yu, Qigui, Hrycyna, Christine A., Chmielewski, Jean

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 669 KB

2019

48

Effects of the quantization ambiguities on the Big Bounce dynamics

Orest Hrycyna, Jakub Mielczarek, Marek Szydłowski

Journal:

General Relativity and Gravitation

Year:

2009

Language:

english

File:

PDF, 800 KB

english, 2009

49

Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer

Hilda A. Namanja, Dana Emmert, Marcos M. Pires, Christine A. Hrycyna, Jean Chmielewski

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 401 KB

english, 2009

50

Both ATP Sites of Human P-Glycoprotein Are Essential but Not Symmetric †

Hrycyna, Christine A., Ramachandra, Muralidhara, Germann, Ursula A., Cheng, Priscilla Wu, Pastan, Ira, Gottesman, Michael M.

Journal:

Year:

1999

Language:

english

File:

PDF, 251 KB

english, 1999

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